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Anthocyanin Tissue Bioavailability in Animals: Possible Implications for Human Health. A Systematic Review
Anthocyanin Tissue Bioavailability in Animals: Possible Implications for Human Health. A Systematic Review
Anthocyanins (ACNs) are promising health-enhancing phenolic compounds. We focus on ACN animal tissue bioavailability to provide an evidentiary link between tissue ACNs and their associated health properties. We performed a systematic review of electronic libraries; 279 results were retrieved, and 13 publications met inclusion criteria. Extracted information included animal model employed, administration route, doses, analysis method, and ACN concentration values in tissues. Total ACN concentrations were detected in mice kidney (2.17 × 105 pmol/g), liver (1.73 × 105 pmol/g), heart (3.6 × 103 pmol/g), and lung (1.16 × 105 pmol/g); and in pig brain (6.08 × 103 pmol/g). ACNs showed a predominance of parent ACNs in long-term experiments versus an ACN metabolite predominance in short-term experiments. ACNs detected in animal tissues, such as cyanidin-3-glucoside, suggest it may have an important role in human health. This information could be useful to determine proper ACN-intake biomarkers in biological samples in futures studies.
Medicina ii, Biotecnología, Planejamento urbano e regional / demografia, Ciências agrárias i, Odontología, Medicina i, Nutrição, phenolic compounds, Food science & technology, Agriculture, multidisciplinary, Anthocyanins, Agricultural and Biological Sciences (Miscellaneous),Agriculture,Agriculture, Multidisciplinary,Chemistry (Miscellaneous),Chemistry, Applied,Food Science & Technology, General chemistry, Ciências biológicas iii, Agricultural and biological sciences (miscellaneous), Ciências ambientais, Zootecnia / recursos pesqueiros, Medicina veterinaria, Engenharias iii, Tissue bioavailability, Engenharias ii, Chemistry (all), Biodiversidade, Healthcare, Astronomia / física, Interdisciplinar, Agriculture, health, Química, Engenharias iv, Chemistry, applied, General medicine, Farmacia, Agricultural and biological sciences (all), anthocyanins, Animal studies, Agricultural sciences, Ensino, Saúde coletiva, Educação, mechanism-of-action, Chemistry (miscellaneous), Ciência de alimentos, General agricultural and biological sciences, Materiais, Ciências biológicas ii, Ciências biológicas i, Ciência da computação
Medicina ii, Biotecnología, Planejamento urbano e regional / demografia, Ciências agrárias i, Odontología, Medicina i, Nutrição, phenolic compounds, Food science & technology, Agriculture, multidisciplinary, Anthocyanins, Agricultural and Biological Sciences (Miscellaneous),Agriculture,Agriculture, Multidisciplinary,Chemistry (Miscellaneous),Chemistry, Applied,Food Science & Technology, General chemistry, Ciências biológicas iii, Agricultural and biological sciences (miscellaneous), Ciências ambientais, Zootecnia / recursos pesqueiros, Medicina veterinaria, Engenharias iii, Tissue bioavailability, Engenharias ii, Chemistry (all), Biodiversidade, Healthcare, Astronomia / física, Interdisciplinar, Agriculture, health, Química, Engenharias iv, Chemistry, applied, General medicine, Farmacia, Agricultural and biological sciences (all), anthocyanins, Animal studies, Agricultural sciences, Ensino, Saúde coletiva, Educação, mechanism-of-action, Chemistry (miscellaneous), Ciência de alimentos, General agricultural and biological sciences, Materiais, Ciências biológicas ii, Ciências biológicas i, Ciência da computação
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!Anthocyanins (ACNs) are promising health-enhancing phenolic compounds. We focus on ACN animal tissue bioavailability to provide an evidentiary link between tissue ACNs and their associated health properties. We performed a systematic review of electronic libraries; 279 results were retrieved, and 13 publications met inclusion criteria. Extracted information included animal model employed, administration route, doses, analysis method, and ACN concentration values in tissues. Total ACN concentrations were detected in mice kidney (2.17 × 105 pmol/g), liver (1.73 × 105 pmol/g), heart (3.6 × 103 pmol/g), and lung (1.16 × 105 pmol/g); and in pig brain (6.08 × 103 pmol/g). ACNs showed a predominance of parent ACNs in long-term experiments versus an ACN metabolite predominance in short-term experiments. ACNs detected in animal tissues, such as cyanidin-3-glucoside, suggest it may have an important role in human health. This information could be useful to determine proper ACN-intake biomarkers in biological samples in futures studies.