In this action, we propose a novel portable and cost-effective multispectral device for smartphones that will monitor dog skin health in terms of erythema. Up to 50-% of European households own a dog, and the five of the ten most common reasons for a veterinary visit can be reflected in erythematous skin. Currently, there are no methods for the objective estimation of the intensity of erythema. In this action, we will first develop multispectral near-infrared device for the detection of extra absorption peaks of hemoglobin. In order to learn about hemodynamics, we will continue with objective measurements of capillary refill time. Then, we will develop a device for the multimodal acquisition of visible multispectral and fluorescence images and near-infrared multispectral data. This will serve for an estimation of erythema intensity by calculating an erythema index. The latter will be validated using existing dermatological tests (e.g. CADESI) in order to study whether erythema index can replace erythema visual assessment. Finally, we will investigate if there is any correlation between erythema and underlying causes (tumors). The proposed methods can simplify and improve current diagnostic procedures in veterinary dermatology. The action will improve the experienced researcher’s knowledge and skills in both fields of his profession: biophotonics and veterinary medicine, which will lead to well integrated interdisciplinary knowledge. This will allow the researcher to address interdisciplinary research challenges much better and, consequently, enhance his future career prospects. Furthermore, he will also obtain additional training to acquire extra professional skills (e.g. mentorship). Moreover, the beneficiary’s biophotonic techniques will be upgraded and promoted in the new scientific field (i.e. veterinary medicine). Additionally, the host will be able to better validate his work with higher number of samples, which will make research in human medicine much safer.
The collective behavior of magnetic particles in rotating fields opens challenging physical questions and suggests their role as model systems for nonlinear behavior in soft matter physics. Their non-equilibrium phase diagrams show a wide range of patterns. From the experimental perspective, the control by an external magnetic field of collective dynamics of particles with permanent dipoles, namely magnetic spinners, offers a promising route for applications such as chiral fluids, cargo transport, and targeted delivery. However, the full comprehensive understanding of pattern control of the magnetic-responsive aggregates remains challenging and it lacks a profound investigation, which is crucial for future applications. This proposal aims to investigate the pattern formation in systems of magnetic spinners by theoretical approaches, which are compared to experimental data, to find characteristic parameters and rules. Studies will make use, of particle-resolved computer simulations such as Langevin Dynamics Simulation, based on Langevin equations to investigate the interplay among magnetic, hydrodynamics, and lubrication interaction.