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description Publicationkeyboard_double_arrow_right Article 2016 United KingdomPublisher:Public Library of Science (PLoS) Publicly fundedFunded by:EC | PROSENSE, EC | GLYCOHIT, SFI | Epigentic Regulation of G... +1 projectsEC| PROSENSE ,EC| GLYCOHIT ,SFI| Epigentic Regulation of Glycosylation and the Impact on Chemo-resistance in Cancer ,Irish Cancer SocietySarah Gilgunn; Silvia Millán Martín; Mark R. Wormald; Julia Zapatero-Rodríguez; Paul J. Conroy; Richard O'Kennedy; Pauline M. Rudd; Radka Saldova;Recent exploitation of the avian immune system has highlighted its suitability for the generation of high-quality, high-affinity antibodies to a wide range of antigens for a number of therapeutic and biotechnological applications. The glycosylation profile of potential immunoglobulin therapeutics is species specific and is heavily influenced by the cell-line/culture conditions used for production. Hence, knowledge of the carbohydrate moieties present on immunoglobulins is essential as certain glycan structures can adversely impact their physicochemical and biological properties. This study describes the detailed N-glycan profile of IgY polyclonal antibodies from the serum of leghorn chickens using a fully quantitative high-throughput N-glycan analysis approach, based on ultra-performance liquid chromatography (UPLC) separation of released glycans. Structural assignments revealed serum IgY to contain complex bi-, tri- and tetra-antennary glycans with or without core fucose and bisects, hybrid and high mannose glycans. High sialic acid content was also observed, with the presence of rare sialic acid structures, likely polysialic acids. It is concluded that IgY is heavily decorated with complex glycans; however, no known non-human or immunogenic glycans were identified. Thus, IgY is a potentially promising candidate for immunoglobulin-based therapies for the treatment of various infectious diseases.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2016Full-Text: http://europepmc.org/articles/PMC4961449Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0159859&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 18 citations 18 popularity Top 10% influence Average impulse Top 10% Powered by BIP!visibility 4visibility views 4 download downloads 94 Powered bymore_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2016Full-Text: http://europepmc.org/articles/PMC4961449Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0159859&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2010 IrelandPublisher:Elsevier BV Publicly fundedFunded by:SFI | CSET CLARITY: Bringing In...SFI| CSET CLARITY: Bringing Information to LifeFay, Cormac; Lau, King-Tong; Beirne, Stephen; Ó Conaire, Ciarán; McGuinness, Kevin; Corcoran, Brian; O'Connor, Noel E.; Diamond, Dermot; McGovern, Scott; Coleman, Greg; Shepherd, Roderick; Alici, Gursel; Spinks, Geoff; Wallace, Gordon;Abstract The cost of monitoring and detecting pollutants in natural waters is of major concern. Current and forthcoming bodies of legislation will continue to drive demand for spatial and selective monitoring of our environment, as the focus increasingly moves towards effective enforcement of legislation through detection of harmful events, and unambiguous identification of perpetrators. However, these monitoring demands are not being met due to the infrastructure and maintenance costs of conventional sensing models. Advanced autonomous platforms capable of performing complex analytical measurements at remote locations still require individual power, wireless communication, processor and electronic transducer units, along with regular maintenance visits. Hence the cost base for these systems is prohibitively high, and the spatial density and frequency of measurements are insufficient to meet requirements. In this paper, we present a more cost effective approach for water quality monitoring using a low cost mobile sensing/communications platform together with very low cost stand-alone ‘satellite’ indicator stations that have an integrated colorimetric sensing material. The mobile platform is equipped with a wireless video camera that is used to interrogate each station to harvest information about the water quality. In simulation experiments, the first cycle of measurements is carried out to identify a ‘normal’ condition followed by a second cycle during which the platform successfully detected and communicated the presence of a chemical contaminant that had been localised at one of the satellite stations.
Sensors and Actuator... arrow_drop_down DCU Online Research Access ServiceArticle . 2010 . Peer-reviewedData sources: DCU Online Research Access ServiceSensors and Actuators B ChemicalArticle . 2010 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.snb.2010.06.021&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routeshybrid 21 citations 21 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Sensors and Actuator... arrow_drop_down DCU Online Research Access ServiceArticle . 2010 . Peer-reviewedData sources: DCU Online Research Access ServiceSensors and Actuators B ChemicalArticle . 2010 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.snb.2010.06.021&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2013 Ireland, AustraliaPublisher:Elsevier BV Publicly fundedFunded by:SFI | SRC StratAG: Strategic Re..., IRCSFI| SRC StratAG: Strategic Research Cluster In Advanced Geotechnologies ,IRCAuthors: Kumar, Pankaj; McElhinney, Conor P.; Lewis, Paul; McCarthy, Tim;Kumar, Pankaj; McElhinney, Conor P.; Lewis, Paul; McCarthy, Tim;handle: 11541.2/142721
Terrestrial mobile laser scanning systems provide rapid and cost effective 3D point cloud data which can be used for extracting features such as the road edge along a route corridor. This information can assist road authorities in carrying out safety risk assessment studies along road networks. The knowledge of the road edge is also a prerequisite for the automatic estimation of most other road features. In this paper, we present an algorithm which has been developed for extracting left and right road edges from terrestrial mobile LiDAR data. The algorithm is based on a novel combination of two modified versions of the parametric active contour or snake model. The parameters involved in the algorithm are selected empirically and are fixed for all the road sections. We have developed a novel way of initialising the snake model based on the navigation information obtained from the mobile mapping vehicle. We tested our algorithm on different types of road sections representing rural, urban and national primary road sections. The successful extraction of road edges from these multiple road section environments validates our algorithm. These findings and knowledge provide valuable insights as well as a prototype road edge extraction tool-set, for both national road authorities and survey companies. Refereed/Peer-reviewed
Maynooth University ... arrow_drop_down Maynooth University ePrints & eTheses ArchiveArticle . 2013 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveUniSA Research Outputs RepositoryArticle . 2013 . Peer-reviewedData sources: UniSA Research Outputs RepositoryISPRS Journal of Photogrammetry and Remote SensingArticle . 2013 . Peer-reviewedData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.isprsjprs.2013.08.003&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 107 citations 107 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Maynooth University ... arrow_drop_down Maynooth University ePrints & eTheses ArchiveArticle . 2013 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveUniSA Research Outputs RepositoryArticle . 2013 . Peer-reviewedData sources: UniSA Research Outputs RepositoryISPRS Journal of Photogrammetry and Remote SensingArticle . 2013 . Peer-reviewedData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.isprsjprs.2013.08.003&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2020Publisher:Public Library of Science (PLoS) Funded by:SFI | Integrated genomics appro...SFI| Integrated genomics approaches to understanding genetic contributions to system-wide exercise physiology parameters in a large animal model.Han, Haige; McGivney, Beatrice A.; Farries, Gabriella; Katz, Lisa M.; MacHugh, David E.; Randhawa, Imtiaz A. S.; Hill, Emmeline W.;Thoroughbred horse racing is a global sport with major hubs in Europe, North America, Australasia and Japan. Regional preferences for certain traits have resulted in phenotypic variation that may result from adaptation to the local racing ecosystem. Here, we test the hypothesis that genes selected for regional phenotypic variation may be identified by analysis of selection signatures in pan-genomic SNP genotype data. Comparing Australian to non-Australian Thoroughbred horses (n = 99), the most highly differentiated loci in a composite selection signals (CSS) analysis were on ECA6 (34.75-34.85 Mb), ECA14 (33.2-33.52 Mb and 35.52-36.94 Mb) and ECA16 (24.28-26.52 Mb) in regions containing candidate genes for exercise adaptations including cardiac function (ARHGAP26, HBEGF, SRA1), synapse development and locomotion (APBB3, ATXN7, CLSTN3), stress response (NR3C1) and the skeletal muscle response to exercise (ARHGAP26, NDUFA2). In a genome-wide association study for field-measured speed in two-year-olds (n = 179) SNPs contained within the single association peak (33.2-35.6 Mb) overlapped with the ECA14 CSS signals and spanned a protocadherin gene cluster. Association tests using higher density SNP genotypes across the ECA14 locus identified a SNP within the PCDHGC5 gene associated with elite racing performance (n = 922). These results indicate that there may be differential selection for racing performance under racing and management conditions that are specific to certain geographic racing regions. In Australia breeders have principally selected horses for favourable genetic variants at loci containing genes that modulate behaviour, locomotion and skeletal muscle physiology that together appear to be contributing to early two-year-old speed.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2020Full-Text: http://europepmc.org/articles/PMC7015314Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0227212&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 11 citations 11 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2020Full-Text: http://europepmc.org/articles/PMC7015314Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0227212&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2017 Ireland, AustraliaPublisher:Institute of Electrical and Electronics Engineers (IEEE) Publicly fundedFunded by:SFI | Novel LiDAR Web services ..., SFI | SRC StratAG: Strategic Re..., IRCSFI| Novel LiDAR Web services for mapping & monitoring Road Network Infrastructure ,SFI| SRC StratAG: Strategic Research Cluster In Advanced Geotechnologies ,IRCPankaj Kumar; Paul H. Lewis; Conor P. McElhinney; Pawel Boguslawski; Timothy J McCarthy;handle: 11541.2/142714
The negative impact of road accidents cannot be ignored in terms of the very sizeable social and economic loss. Road infrastructure has been identified as one of the main causes of the road accidents. They are required to be recorded, located, measured, and classified in order to schedule maintenance and identify the possible risk elements of the road. Toward this, an accurate knowledge of the road edges increases the reliability and precision of extracting other road features. We have developed an automated algorithm for extracting road edges from mobile laser scanning (MLS) data based on the parametric active contour or snake model. The algorithm involves several internal and external energy parameters that need to be analyzed in order to find their optimal values. In this paper, we present a detailed analysis of the snake energy parameters involved in our road edge extraction algorithm. Their optimal values enable us to automate the process of extracting edges from MLS data for tested road sections. We present a modified external energy in our algorithm and demonstrate its utility for extracting road edges from low and nonuniform point density datasets. A novel validation approach is presented, which provides a qualitative assessment of the extracted road edges based on direct comparisons with reference road edges. This approach provides an alternative to traditional road edge validation methodologies that are based on creating buffer zones around reference road edges and then computing quality measure values for the extracted edges. We tested our road edge extraction algorithm on datasets that were acquired using multiple MLS systems along various complex road sections. The successful extraction of road edges from these datasets validates the robustness of our algorithm for use in complex route corridor environments. Refereed/Peer-reviewed
CORE (RIOXX-UK Aggre... arrow_drop_down CORE (RIOXX-UK Aggregator)Article . 2017License: rioxx All Rights ReservedData sources: CORE (RIOXX-UK Aggregator)Maynooth University ePrints & eTheses ArchiveArticle . 2016 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveIEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingArticleLicense: CC BYData sources: UnpayWallIEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingArticle . 2017 . Peer-reviewedLicense: IEEE CopyrightData sources: CrossrefUniSA Research Outputs RepositoryArticle . 2017 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/jstars.2016.2564984&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 15 citations 15 popularity Top 10% influence Average impulse Top 10% Powered by BIP!visibility 31visibility views 31 download downloads 137 Powered bymore_vert CORE (RIOXX-UK Aggre... arrow_drop_down CORE (RIOXX-UK Aggregator)Article . 2017License: rioxx All Rights ReservedData sources: CORE (RIOXX-UK Aggregator)Maynooth University ePrints & eTheses ArchiveArticle . 2016 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveIEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingArticleLicense: CC BYData sources: UnpayWallIEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingArticle . 2017 . Peer-reviewedLicense: IEEE CopyrightData sources: CrossrefUniSA Research Outputs RepositoryArticle . 2017 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1109/jstars.2016.2564984&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 IrelandPublisher:Public Library of Science (PLoS) Publicly fundedFunded by:SFI | VistaMilk Centre, SFI | Precision cattle breeding...SFI| VistaMilk Centre ,SFI| Precision cattle breeding using precision genomicsS.C. Ring; D. C. Purfield; Margaret Good; P. Breslin; E. Ryan; Astrid Blom; Ross D Evans; Michael L. Doherty; Daniel G. Bradley; Donagh P. Berry;peer-reviewed Bovine tuberculosis (bTB) is an infectious disease of cattle generally caused by Mycobacterium bovis, a bacterium that can elicit disease humans. Since the 1950s, the objective of the national bTB eradication program in Republic of Ireland was the biological extinction of bTB; that purpose has yet to be achieved. Objectives of the present study were to develop the statistical methodology and variance components to undertake routine genetic evaluations for resistance to bTB; also of interest was the detection of regions of the bovine genome putatively associated with bTB infection in dairy and beef breeds. The novelty of the present study, in terms of research on bTB infection, was the use of beef breeds in the genome-wide association and the utilization of imputed whole genome sequence data. Phenotypic bTB data on 781,270 animals together with imputed whole genome sequence data on 7,346 of these animals’ sires were available. Linear mixed models were used to quantify variance components for bTB and EBVs were validated. Within-breed and multi-breed genome-wide associations were undertaken using a single-SNP regression approach. The estimated genetic standard deviation (0.09), heritability (0.12), and repeatability (0.30) substantiate that genetic selection help to eradicate bTB. The multi-breed genome-wide association analysis identified 38 SNPs and 64 QTL regions associated with bTB infection; two QTL regions (both on BTA23) identified in the multi-breed analysis overlapped with the within-breed analyses of Charolais, Limousin, and Holstein-Friesian. Results from the association analysis, coupled with previous studies, suggest bTB is controlled by an infinitely large number of loci, each having a small effect. The methodology and results from the present study will be used to develop national genetic evaluations for bTB in the Republic of Ireland. In addition, results can also be used to help uncover the biological architecture underlying resistance to bTB infection in cattle.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6375599Data sources: PubMed CentralTrinity's Access to Research ArchiveArticle . 2019 . Peer-reviewedData sources: Trinity's Access to Research Archiveadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0212067&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 24 citations 24 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6375599Data sources: PubMed CentralTrinity's Access to Research ArchiveArticle . 2019 . Peer-reviewedData sources: Trinity's Access to Research Archiveadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0212067&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2013 DenmarkPublisher:MDPI AG Publicly fundedFunded by:SFI | CSET BDI: Biomedical Diag...SFI| CSET BDI: Biomedical Diagnostics InstituteNwankire, Charles; Chan, Di-Sien; Gaughran, Jennifer; Burger, Robert; Gorkin, Robert; Ducrée, Jens;This paper demonstrates the full centrifugal microfluidic integration and automation of all liquid handling steps of a 7-step fluorescence-linked immunosorbent assay (FLISA) for quantifying nitrate and nitrite levels in whole blood within about 15 min. The assay protocol encompasses the extraction of metered plasma, the controlled release of sample and reagents (enzymes, co-factors and fluorescent labels), and incubation and detection steps. Flow control is implemented by a rotationally actuated dissolvable film (DF) valving scheme. In the valves, the burst pressure is primarily determined by the radial position, geometry and volume of the valve chamber and its inlet channel and can thus be individually tuned over an extraordinarily wide range of equivalent spin rates between 1,000 RPM and 5,500 RPM. Furthermore, the vapour barrier properties of the DF valves are investigated in this paper in order to further show the potential for commercially relevant on-board storage of liquid reagents during shelf-life of bioanalytical, ready-to-use discs. © 2013 by the authors; licensee MDPI, Basel, Switzerland.
Sensors arrow_drop_down SensorsOther literature type . Article . 2013 . Peer-reviewedLicense: CC BYFull-Text: http://www.mdpi.com/1424-8220/13/9/11336/pdfEurope PubMed CentralArticle . 2013Full-Text: http://europepmc.org/articles/PMC3821360Data sources: PubMed CentralOnline Research Database In TechnologyArticle . 2013Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/s130911336&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 23 citations 23 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Sensors arrow_drop_down SensorsOther literature type . Article . 2013 . Peer-reviewedLicense: CC BYFull-Text: http://www.mdpi.com/1424-8220/13/9/11336/pdfEurope PubMed CentralArticle . 2013Full-Text: http://europepmc.org/articles/PMC3821360Data sources: PubMed CentralOnline Research Database In TechnologyArticle . 2013Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/s130911336&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2023 IrelandPublisher:Elsevier BV Publicly fundedFunded by:NSF | Collaborative Research: A..., Trinity College Dublin, NSF | Collaborative Research: A... +2 projectsNSF| Collaborative Research: Accel-Net: Nature-Based Solutions for Urban Resilience in the Anthropocene (NATURA) ,Trinity College Dublin ,NSF| Collaborative Research: Accel-Net: Nature-Based Solutions for Urban Resilience in the Anthropocene (NATURA) ,SFI| ADAPT_Phase 2 ,EC| NovelEcoPineda-Pinto, Melissa; Kennedy, Christopher; Collier, Marcus J.; Cooper, Clair; O'Donnell, Mairéad; Nulty, Fiona; Rodriguez Castañeda, Natalia;handle: 2262/103000
PUBLISHED Though most cities, particularly in the Global North, have been intensely modified by human activities certain locations still exist in varied forms of abandonment or disinvestment, often allowing for new species assemblages to flourish. These urban novel ecosystems or informal wild spaces are often perceived as in-between or overlooked, calling into question their value and social-ecological role, while also creating tensions amongst different groups and stakeholders who share different visions for their use and management. Within these tensions, issues of justice and equity can be more pronounced and surface historic legacies of environmental contamination, inequitable development, and extraction. Despite this, very little is known about the social-ecological role informal wild spaces play in urban areas, and how best to interrogate and understand the equity and justice dimensions they elicit. To fill this gap in knowledge, this paper critically examines the literature on urban novel ecosystems in relation to justice, with a particular interest in multispecies justice. Through this analysis, gaps in the literature are exposed, while also arguing the informality, neglect and contestation of wild urban spaces provides opportunities to explore issues of access, benefits and harms, particularly in light of global climate and ecological crises. A systematic approach is utilized to search the literature, identifying 45 papers which are thematically analyzed under a justice lens. The study identifies three themes that thread throughout the literature: distributional injustices relate to perceptions and attitudes, which give rise or arise from injustices; the regeneration discourse focuses on a ?new nature?, which is based on social-ecological displacement and devaluation; and the potential of urban wild spaces to generate new multispecies sensibilities. The paper concludes by discussing trends, gaps, and emerging discourses, and proposing a multispecies justice approach for urban planning through the learnings and engagement with urban wild, novel ecosystems. Mainstreaming nature-based solutions in cities has grown in scale and magnitude in recent times but is still considered to be the main challenge for transitioning our cities and their communities to be more climate resilient and liveable: environmentally, economically, and socially. Furthermore, taking nature-based solutions to the next level, and scaling them out to all urban contexts to achieve a greater impact, is proving to be slow and often conflicts with other transitioning initiatives such as energy generation, mobility and transport initiatives, and infilling to combat sprawl. So, the task is neither easy nor straightforward; there are many barriers to this novel transition, especially when it comes to collaborative approaches to implementing nature-based solutions with diverse urban communities and within city authorities themselves. This paper reports on a new process that is systematically co-produced and captured as a framework for planning nature-based solutions that emerged during the Connecting Nature project. The Connecting Nature Framework is a three-stage, iterative process that involves seven key activity areas for mainstreaming nature-based solutions: technical solutions, governance, financing and business models, nature-based enterprises, co-production, reflexive monitoring, and impact assessment. The tested and applied framework is designed to address and overcome barriers to the implementation of nature-based solutions in cities via a co-created, iterative, and reflective approach. The planning process guided by the proposed framework has already yielded promising results with some of the cities of the project, though further usage and its adoption by other cities is needed to explore its potential in different contexts especially in the Global South. The paper concludes with suggestions on how this may be realised.
Trinity's Access to ... arrow_drop_down Trinity's Access to Research ArchiveArticle . 2023 . Peer-reviewedData sources: Trinity's Access to Research Archiveadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 3 citations 3 popularity Average influence Average impulse Average Powered by BIP!visibility 8visibility views 8 download downloads 22 Powered bymore_vert Trinity's Access to ... arrow_drop_down Trinity's Access to Research ArchiveArticle . 2023 . Peer-reviewedData sources: Trinity's Access to Research Archiveadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2015 Ireland, AustraliaPublisher:Wiley Publicly fundedFunded by:SFI | SRC StratAG: Strategic Re..., IRCSFI| SRC StratAG: Strategic Research Cluster In Advanced Geotechnologies ,IRCAuthors: Kumar, Pankaj; Lewis, Paul; McElhinney, Conor P.; Rahman, Alias Abdull;Kumar, Pankaj; Lewis, Paul; McElhinney, Conor P.; Rahman, Alias Abdull;doi: 10.1111/phor.12090
handle: 11541.2/142715
Road roughness is the deviation of a road surface from a designed surface grade that influences safety conditions for road users. Mobile laser scanning (MLS) systems provide a rapid, continuous and cost-effective way of collecting highly accurate and dense 3D point-cloud data along a route corridor. In this paper an algorithm for the automated estimation of road roughness from MLS data is presented, where a surface grid is fitted to the lidar points associated with the road surface. The elevation difference between the lidar points and their surface grid equivalents provides residual values in height which can be used to estimate roughness along the road surface. Tests validated the new road-roughness algorithm by successfully estimating surface conditions on multiple road sections. These findings contribute to a more comprehensive approach to surveying road networks. Resume La rugosite d'une route est la deviation de la surface de la route par rapport a la surface concue, qui influence les conditions de securite pour les usagers de la route. Le balayage laser mobile (MLS) offre un moyen rapide, continu et rentable pour recueillir des nuages de points 3D tres precis et denses le long d'une route. Cet article presente un algorithme pour l'estimation automatique de la rugosite de la route a partir de donnees MLS, ou une grille est ajustee sur les points lidar censes representer la surface de la route. La difference entre les altitudes des points lidar et de leurs equivalents dans la grille fournit des valeurs residuelles de hauteur qui peuvent etre utilisees pour estimer la rugosite a la surface de la route. Des tests ont valide ce nouvel algorithme en estimant les caracteristiques de la surface sur de multiples sections de route. Ces resultats contribuent a une approche plus globale du releve topographique des reseaux routiers. Zusammenfassung Die Rauhigkeit einer Strassenoberflache ist die qualitative Abweichung der tatsachlichen Oberflache von der geplanten Oberflache. Eine solche Abweichung beeinflust die Sicherheitsbedingungen fur Strasennutzer. Mit Mobile Laserscanning Systemen (MLS) konnen schnell, kontinuierlich und auf kostengunstige Weise hochgenaue und dichte 3D-Punktwolken entlang eines Strasenkorridors erfasst werden. Dieses Paper stellt einen Algorithmus zur automatischen Bestimmung der Oberflachenrauhigkeit in MLS Daten vor. Ein Oberflachenraster wird an die Punkte der Strasenoberflache angepasst. Die Residuen zwischen Lidarpunkten und den entsprechenden Hohen des angepasten Gitters konnen zur Schatzung der Rauhigkeit verwendet werden. In Tests mit verschiedenen Strasenabschnitten wurde der neue Algorithmus hinsichtlich der Schatzung der Oberflachenbeschaffenheit validiert. Auf Basis dieser Ergebnisse kann ein noch umfassender Ansatz zur Erfassung von ganzen Strasennetzen angegangen werden. Resumen La rugosidad de una carretera es la desviacion de la superficie disenada que afecta las condiciones de seguridad de los usuarios de la carretera. Los sistemas de laser moviles proporcionan una manera rapida, continua y barata de recolectar nubes de puntos 3-D densas y de gran precision a lo largo de un corredor. En este articulo se presenta un algoritmo para la estimacion automatica de la rugosidad de la carretera, donde una malla se ajusta a los puntos lidar asociados con la superficie de la carretera. La diferencia entre la elevacion de los puntos lidar y los equivalentes en la malla proporcionan residuos en altura usados para estimar la rugosidad de la superficie a lo largo de la carretera. Las comprobaciones validan el nuevo algoritmo de rugosidad de la carretera al estimar con exito las condiciones de la carretera en diversas secciones de carretera. Estos resultados contribuyen a un enfoque mas amplio de la medida de las caracteristicas de redes de carreteras. 摘要 路面平整度是衡量道路表面和设计表面之差的等级,对道路使用者的安全条件的度量。移动激光扫描(MLS)系统提供了一种快速获取低成本、高精确和高密度的沿着路线走廊的连续三维点云数据的方式。本文提出从MLS数据自动估计路面平整度的算法,该算法利用一个路面格网来拟合激光点云,两者之间在高程上的残差值可以被用来衡量路面平整度。试验充分验证了本文所提出的新算法针对多路段路面平整度处理的可靠性,本文的这些发现为路网测量提供了一种更全面的手段。
Maynooth University ... arrow_drop_down Maynooth University ePrints & eTheses ArchiveArticle . 2015 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveThe Photogrammetric RecordArticle . 2015 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniSA Research Outputs RepositoryArticle . 2015 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesbronze 22 citations 22 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Maynooth University ... arrow_drop_down Maynooth University ePrints & eTheses ArchiveArticle . 2015 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveThe Photogrammetric RecordArticle . 2015 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniSA Research Outputs RepositoryArticle . 2015 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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description Publicationkeyboard_double_arrow_right Article 2016 United KingdomPublisher:Public Library of Science (PLoS) Publicly fundedFunded by:EC | PROSENSE, EC | GLYCOHIT, SFI | Epigentic Regulation of G... +1 projectsEC| PROSENSE ,EC| GLYCOHIT ,SFI| Epigentic Regulation of Glycosylation and the Impact on Chemo-resistance in Cancer ,Irish Cancer SocietySarah Gilgunn; Silvia Millán Martín; Mark R. Wormald; Julia Zapatero-Rodríguez; Paul J. Conroy; Richard O'Kennedy; Pauline M. Rudd; Radka Saldova;Recent exploitation of the avian immune system has highlighted its suitability for the generation of high-quality, high-affinity antibodies to a wide range of antigens for a number of therapeutic and biotechnological applications. The glycosylation profile of potential immunoglobulin therapeutics is species specific and is heavily influenced by the cell-line/culture conditions used for production. Hence, knowledge of the carbohydrate moieties present on immunoglobulins is essential as certain glycan structures can adversely impact their physicochemical and biological properties. This study describes the detailed N-glycan profile of IgY polyclonal antibodies from the serum of leghorn chickens using a fully quantitative high-throughput N-glycan analysis approach, based on ultra-performance liquid chromatography (UPLC) separation of released glycans. Structural assignments revealed serum IgY to contain complex bi-, tri- and tetra-antennary glycans with or without core fucose and bisects, hybrid and high mannose glycans. High sialic acid content was also observed, with the presence of rare sialic acid structures, likely polysialic acids. It is concluded that IgY is heavily decorated with complex glycans; however, no known non-human or immunogenic glycans were identified. Thus, IgY is a potentially promising candidate for immunoglobulin-based therapies for the treatment of various infectious diseases.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2016Full-Text: http://europepmc.org/articles/PMC4961449Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 18 citations 18 popularity Top 10% influence Average impulse Top 10% Powered by BIP!visibility 4visibility views 4 download downloads 94 Powered bymore_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2016Full-Text: http://europepmc.org/articles/PMC4961449Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2010 IrelandPublisher:Elsevier BV Publicly fundedFunded by:SFI | CSET CLARITY: Bringing In...SFI| CSET CLARITY: Bringing Information to LifeFay, Cormac; Lau, King-Tong; Beirne, Stephen; Ó Conaire, Ciarán; McGuinness, Kevin; Corcoran, Brian; O'Connor, Noel E.; Diamond, Dermot; McGovern, Scott; Coleman, Greg; Shepherd, Roderick; Alici, Gursel; Spinks, Geoff; Wallace, Gordon;Abstract The cost of monitoring and detecting pollutants in natural waters is of major concern. Current and forthcoming bodies of legislation will continue to drive demand for spatial and selective monitoring of our environment, as the focus increasingly moves towards effective enforcement of legislation through detection of harmful events, and unambiguous identification of perpetrators. However, these monitoring demands are not being met due to the infrastructure and maintenance costs of conventional sensing models. Advanced autonomous platforms capable of performing complex analytical measurements at remote locations still require individual power, wireless communication, processor and electronic transducer units, along with regular maintenance visits. Hence the cost base for these systems is prohibitively high, and the spatial density and frequency of measurements are insufficient to meet requirements. In this paper, we present a more cost effective approach for water quality monitoring using a low cost mobile sensing/communications platform together with very low cost stand-alone ‘satellite’ indicator stations that have an integrated colorimetric sensing material. The mobile platform is equipped with a wireless video camera that is used to interrogate each station to harvest information about the water quality. In simulation experiments, the first cycle of measurements is carried out to identify a ‘normal’ condition followed by a second cycle during which the platform successfully detected and communicated the presence of a chemical contaminant that had been localised at one of the satellite stations.
Sensors and Actuator... arrow_drop_down DCU Online Research Access ServiceArticle . 2010 . Peer-reviewedData sources: DCU Online Research Access ServiceSensors and Actuators B ChemicalArticle . 2010 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routeshybrid 21 citations 21 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Sensors and Actuator... arrow_drop_down DCU Online Research Access ServiceArticle . 2010 . Peer-reviewedData sources: DCU Online Research Access ServiceSensors and Actuators B ChemicalArticle . 2010 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.snb.2010.06.021&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2013 Ireland, AustraliaPublisher:Elsevier BV Publicly fundedFunded by:SFI | SRC StratAG: Strategic Re..., IRCSFI| SRC StratAG: Strategic Research Cluster In Advanced Geotechnologies ,IRCAuthors: Kumar, Pankaj; McElhinney, Conor P.; Lewis, Paul; McCarthy, Tim;Kumar, Pankaj; McElhinney, Conor P.; Lewis, Paul; McCarthy, Tim;handle: 11541.2/142721
Terrestrial mobile laser scanning systems provide rapid and cost effective 3D point cloud data which can be used for extracting features such as the road edge along a route corridor. This information can assist road authorities in carrying out safety risk assessment studies along road networks. The knowledge of the road edge is also a prerequisite for the automatic estimation of most other road features. In this paper, we present an algorithm which has been developed for extracting left and right road edges from terrestrial mobile LiDAR data. The algorithm is based on a novel combination of two modified versions of the parametric active contour or snake model. The parameters involved in the algorithm are selected empirically and are fixed for all the road sections. We have developed a novel way of initialising the snake model based on the navigation information obtained from the mobile mapping vehicle. We tested our algorithm on different types of road sections representing rural, urban and national primary road sections. The successful extraction of road edges from these multiple road section environments validates our algorithm. These findings and knowledge provide valuable insights as well as a prototype road edge extraction tool-set, for both national road authorities and survey companies. Refereed/Peer-reviewed
Maynooth University ... arrow_drop_down Maynooth University ePrints & eTheses ArchiveArticle . 2013 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveUniSA Research Outputs RepositoryArticle . 2013 . Peer-reviewedData sources: UniSA Research Outputs RepositoryISPRS Journal of Photogrammetry and Remote SensingArticle . 2013 . Peer-reviewedData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.isprsjprs.2013.08.003&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 107 citations 107 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Maynooth University ... arrow_drop_down Maynooth University ePrints & eTheses ArchiveArticle . 2013 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveUniSA Research Outputs RepositoryArticle . 2013 . Peer-reviewedData sources: UniSA Research Outputs RepositoryISPRS Journal of Photogrammetry and Remote SensingArticle . 2013 . Peer-reviewedData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.isprsjprs.2013.08.003&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2020Publisher:Public Library of Science (PLoS) Funded by:SFI | Integrated genomics appro...SFI| Integrated genomics approaches to understanding genetic contributions to system-wide exercise physiology parameters in a large animal model.Han, Haige; McGivney, Beatrice A.; Farries, Gabriella; Katz, Lisa M.; MacHugh, David E.; Randhawa, Imtiaz A. S.; Hill, Emmeline W.;Thoroughbred horse racing is a global sport with major hubs in Europe, North America, Australasia and Japan. Regional preferences for certain traits have resulted in phenotypic variation that may result from adaptation to the local racing ecosystem. Here, we test the hypothesis that genes selected for regional phenotypic variation may be identified by analysis of selection signatures in pan-genomic SNP genotype data. Comparing Australian to non-Australian Thoroughbred horses (n = 99), the most highly differentiated loci in a composite selection signals (CSS) analysis were on ECA6 (34.75-34.85 Mb), ECA14 (33.2-33.52 Mb and 35.52-36.94 Mb) and ECA16 (24.28-26.52 Mb) in regions containing candidate genes for exercise adaptations including cardiac function (ARHGAP26, HBEGF, SRA1), synapse development and locomotion (APBB3, ATXN7, CLSTN3), stress response (NR3C1) and the skeletal muscle response to exercise (ARHGAP26, NDUFA2). In a genome-wide association study for field-measured speed in two-year-olds (n = 179) SNPs contained within the single association peak (33.2-35.6 Mb) overlapped with the ECA14 CSS signals and spanned a protocadherin gene cluster. Association tests using higher density SNP genotypes across the ECA14 locus identified a SNP within the PCDHGC5 gene associated with elite racing performance (n = 922). These results indicate that there may be differential selection for racing performance under racing and management conditions that are specific to certain geographic racing regions. In Australia breeders have principally selected horses for favourable genetic variants at loci containing genes that modulate behaviour, locomotion and skeletal muscle physiology that together appear to be contributing to early two-year-old speed.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2020Full-Text: http://europepmc.org/articles/PMC7015314Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 11 citations 11 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2020Full-Text: http://europepmc.org/articles/PMC7015314Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2017 Ireland, AustraliaPublisher:Institute of Electrical and Electronics Engineers (IEEE) Publicly fundedFunded by:SFI | Novel LiDAR Web services ..., SFI | SRC StratAG: Strategic Re..., IRCSFI| Novel LiDAR Web services for mapping & monitoring Road Network Infrastructure ,SFI| SRC StratAG: Strategic Research Cluster In Advanced Geotechnologies ,IRCPankaj Kumar; Paul H. Lewis; Conor P. McElhinney; Pawel Boguslawski; Timothy J McCarthy;handle: 11541.2/142714
The negative impact of road accidents cannot be ignored in terms of the very sizeable social and economic loss. Road infrastructure has been identified as one of the main causes of the road accidents. They are required to be recorded, located, measured, and classified in order to schedule maintenance and identify the possible risk elements of the road. Toward this, an accurate knowledge of the road edges increases the reliability and precision of extracting other road features. We have developed an automated algorithm for extracting road edges from mobile laser scanning (MLS) data based on the parametric active contour or snake model. The algorithm involves several internal and external energy parameters that need to be analyzed in order to find their optimal values. In this paper, we present a detailed analysis of the snake energy parameters involved in our road edge extraction algorithm. Their optimal values enable us to automate the process of extracting edges from MLS data for tested road sections. We present a modified external energy in our algorithm and demonstrate its utility for extracting road edges from low and nonuniform point density datasets. A novel validation approach is presented, which provides a qualitative assessment of the extracted road edges based on direct comparisons with reference road edges. This approach provides an alternative to traditional road edge validation methodologies that are based on creating buffer zones around reference road edges and then computing quality measure values for the extracted edges. We tested our road edge extraction algorithm on datasets that were acquired using multiple MLS systems along various complex road sections. The successful extraction of road edges from these datasets validates the robustness of our algorithm for use in complex route corridor environments. Refereed/Peer-reviewed
CORE (RIOXX-UK Aggre... arrow_drop_down CORE (RIOXX-UK Aggregator)Article . 2017License: rioxx All Rights ReservedData sources: CORE (RIOXX-UK Aggregator)Maynooth University ePrints & eTheses ArchiveArticle . 2016 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveIEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingArticleLicense: CC BYData sources: UnpayWallIEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingArticle . 2017 . Peer-reviewedLicense: IEEE CopyrightData sources: CrossrefUniSA Research Outputs RepositoryArticle . 2017 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 15 citations 15 popularity Top 10% influence Average impulse Top 10% Powered by BIP!visibility 31visibility views 31 download downloads 137 Powered bymore_vert CORE (RIOXX-UK Aggre... arrow_drop_down CORE (RIOXX-UK Aggregator)Article . 2017License: rioxx All Rights ReservedData sources: CORE (RIOXX-UK Aggregator)Maynooth University ePrints & eTheses ArchiveArticle . 2016 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveIEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingArticleLicense: CC BYData sources: UnpayWallIEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingArticle . 2017 . Peer-reviewedLicense: IEEE CopyrightData sources: CrossrefUniSA Research Outputs RepositoryArticle . 2017 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 IrelandPublisher:Public Library of Science (PLoS) Publicly fundedFunded by:SFI | VistaMilk Centre, SFI | Precision cattle breeding...SFI| VistaMilk Centre ,SFI| Precision cattle breeding using precision genomicsS.C. Ring; D. C. Purfield; Margaret Good; P. Breslin; E. Ryan; Astrid Blom; Ross D Evans; Michael L. Doherty; Daniel G. Bradley; Donagh P. Berry;peer-reviewed Bovine tuberculosis (bTB) is an infectious disease of cattle generally caused by Mycobacterium bovis, a bacterium that can elicit disease humans. Since the 1950s, the objective of the national bTB eradication program in Republic of Ireland was the biological extinction of bTB; that purpose has yet to be achieved. Objectives of the present study were to develop the statistical methodology and variance components to undertake routine genetic evaluations for resistance to bTB; also of interest was the detection of regions of the bovine genome putatively associated with bTB infection in dairy and beef breeds. The novelty of the present study, in terms of research on bTB infection, was the use of beef breeds in the genome-wide association and the utilization of imputed whole genome sequence data. Phenotypic bTB data on 781,270 animals together with imputed whole genome sequence data on 7,346 of these animals’ sires were available. Linear mixed models were used to quantify variance components for bTB and EBVs were validated. Within-breed and multi-breed genome-wide associations were undertaken using a single-SNP regression approach. The estimated genetic standard deviation (0.09), heritability (0.12), and repeatability (0.30) substantiate that genetic selection help to eradicate bTB. The multi-breed genome-wide association analysis identified 38 SNPs and 64 QTL regions associated with bTB infection; two QTL regions (both on BTA23) identified in the multi-breed analysis overlapped with the within-breed analyses of Charolais, Limousin, and Holstein-Friesian. Results from the association analysis, coupled with previous studies, suggest bTB is controlled by an infinitely large number of loci, each having a small effect. The methodology and results from the present study will be used to develop national genetic evaluations for bTB in the Republic of Ireland. In addition, results can also be used to help uncover the biological architecture underlying resistance to bTB infection in cattle.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6375599Data sources: PubMed CentralTrinity's Access to Research ArchiveArticle . 2019 . Peer-reviewedData sources: Trinity's Access to Research Archiveadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0212067&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 24 citations 24 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6375599Data sources: PubMed CentralTrinity's Access to Research ArchiveArticle . 2019 . Peer-reviewedData sources: Trinity's Access to Research Archiveadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0212067&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2013 DenmarkPublisher:MDPI AG Publicly fundedFunded by:SFI | CSET BDI: Biomedical Diag...SFI| CSET BDI: Biomedical Diagnostics InstituteNwankire, Charles; Chan, Di-Sien; Gaughran, Jennifer; Burger, Robert; Gorkin, Robert; Ducrée, Jens;This paper demonstrates the full centrifugal microfluidic integration and automation of all liquid handling steps of a 7-step fluorescence-linked immunosorbent assay (FLISA) for quantifying nitrate and nitrite levels in whole blood within about 15 min. The assay protocol encompasses the extraction of metered plasma, the controlled release of sample and reagents (enzymes, co-factors and fluorescent labels), and incubation and detection steps. Flow control is implemented by a rotationally actuated dissolvable film (DF) valving scheme. In the valves, the burst pressure is primarily determined by the radial position, geometry and volume of the valve chamber and its inlet channel and can thus be individually tuned over an extraordinarily wide range of equivalent spin rates between 1,000 RPM and 5,500 RPM. Furthermore, the vapour barrier properties of the DF valves are investigated in this paper in order to further show the potential for commercially relevant on-board storage of liquid reagents during shelf-life of bioanalytical, ready-to-use discs. © 2013 by the authors; licensee MDPI, Basel, Switzerland.
Sensors arrow_drop_down SensorsOther literature type . Article . 2013 . Peer-reviewedLicense: CC BYFull-Text: http://www.mdpi.com/1424-8220/13/9/11336/pdfEurope PubMed CentralArticle . 2013Full-Text: http://europepmc.org/articles/PMC3821360Data sources: PubMed CentralOnline Research Database In TechnologyArticle . 2013Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/s130911336&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 23 citations 23 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Sensors arrow_drop_down SensorsOther literature type . Article . 2013 . Peer-reviewedLicense: CC BYFull-Text: http://www.mdpi.com/1424-8220/13/9/11336/pdfEurope PubMed CentralArticle . 2013Full-Text: http://europepmc.org/articles/PMC3821360Data sources: PubMed CentralOnline Research Database In TechnologyArticle . 2013Data sources: Online Research Database In Technologyadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/s130911336&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2023 IrelandPublisher:Elsevier BV Publicly fundedFunded by:NSF | Collaborative Research: A..., Trinity College Dublin, NSF | Collaborative Research: A... +2 projectsNSF| Collaborative Research: Accel-Net: Nature-Based Solutions for Urban Resilience in the Anthropocene (NATURA) ,Trinity College Dublin ,NSF| Collaborative Research: Accel-Net: Nature-Based Solutions for Urban Resilience in the Anthropocene (NATURA) ,SFI| ADAPT_Phase 2 ,EC| NovelEcoPineda-Pinto, Melissa; Kennedy, Christopher; Collier, Marcus J.; Cooper, Clair; O'Donnell, Mairéad; Nulty, Fiona; Rodriguez Castañeda, Natalia;handle: 2262/103000
PUBLISHED Though most cities, particularly in the Global North, have been intensely modified by human activities certain locations still exist in varied forms of abandonment or disinvestment, often allowing for new species assemblages to flourish. These urban novel ecosystems or informal wild spaces are often perceived as in-between or overlooked, calling into question their value and social-ecological role, while also creating tensions amongst different groups and stakeholders who share different visions for their use and management. Within these tensions, issues of justice and equity can be more pronounced and surface historic legacies of environmental contamination, inequitable development, and extraction. Despite this, very little is known about the social-ecological role informal wild spaces play in urban areas, and how best to interrogate and understand the equity and justice dimensions they elicit. To fill this gap in knowledge, this paper critically examines the literature on urban novel ecosystems in relation to justice, with a particular interest in multispecies justice. Through this analysis, gaps in the literature are exposed, while also arguing the informality, neglect and contestation of wild urban spaces provides opportunities to explore issues of access, benefits and harms, particularly in light of global climate and ecological crises. A systematic approach is utilized to search the literature, identifying 45 papers which are thematically analyzed under a justice lens. The study identifies three themes that thread throughout the literature: distributional injustices relate to perceptions and attitudes, which give rise or arise from injustices; the regeneration discourse focuses on a ?new nature?, which is based on social-ecological displacement and devaluation; and the potential of urban wild spaces to generate new multispecies sensibilities. The paper concludes by discussing trends, gaps, and emerging discourses, and proposing a multispecies justice approach for urban planning through the learnings and engagement with urban wild, novel ecosystems. Mainstreaming nature-based solutions in cities has grown in scale and magnitude in recent times but is still considered to be the main challenge for transitioning our cities and their communities to be more climate resilient and liveable: environmentally, economically, and socially. Furthermore, taking nature-based solutions to the next level, and scaling them out to all urban contexts to achieve a greater impact, is proving to be slow and often conflicts with other transitioning initiatives such as energy generation, mobility and transport initiatives, and infilling to combat sprawl. So, the task is neither easy nor straightforward; there are many barriers to this novel transition, especially when it comes to collaborative approaches to implementing nature-based solutions with diverse urban communities and within city authorities themselves. This paper reports on a new process that is systematically co-produced and captured as a framework for planning nature-based solutions that emerged during the Connecting Nature project. The Connecting Nature Framework is a three-stage, iterative process that involves seven key activity areas for mainstreaming nature-based solutions: technical solutions, governance, financing and business models, nature-based enterprises, co-production, reflexive monitoring, and impact assessment. The tested and applied framework is designed to address and overcome barriers to the implementation of nature-based solutions in cities via a co-created, iterative, and reflective approach. The planning process guided by the proposed framework has already yielded promising results with some of the cities of the project, though further usage and its adoption by other cities is needed to explore its potential in different contexts especially in the Global South. The paper concludes with suggestions on how this may be realised.
Trinity's Access to ... arrow_drop_down Trinity's Access to Research ArchiveArticle . 2023 . Peer-reviewedData sources: Trinity's Access to Research Archiveadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.ufug.2023.127902&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 3 citations 3 popularity Average influence Average impulse Average Powered by BIP!visibility 8visibility views 8 download downloads 22 Powered bymore_vert Trinity's Access to ... arrow_drop_down Trinity's Access to Research ArchiveArticle . 2023 . Peer-reviewedData sources: Trinity's Access to Research Archiveadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.ufug.2023.127902&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2015 Ireland, AustraliaPublisher:Wiley Publicly fundedFunded by:SFI | SRC StratAG: Strategic Re..., IRCSFI| SRC StratAG: Strategic Research Cluster In Advanced Geotechnologies ,IRCAuthors: Kumar, Pankaj; Lewis, Paul; McElhinney, Conor P.; Rahman, Alias Abdull;Kumar, Pankaj; Lewis, Paul; McElhinney, Conor P.; Rahman, Alias Abdull;doi: 10.1111/phor.12090
handle: 11541.2/142715
Road roughness is the deviation of a road surface from a designed surface grade that influences safety conditions for road users. Mobile laser scanning (MLS) systems provide a rapid, continuous and cost-effective way of collecting highly accurate and dense 3D point-cloud data along a route corridor. In this paper an algorithm for the automated estimation of road roughness from MLS data is presented, where a surface grid is fitted to the lidar points associated with the road surface. The elevation difference between the lidar points and their surface grid equivalents provides residual values in height which can be used to estimate roughness along the road surface. Tests validated the new road-roughness algorithm by successfully estimating surface conditions on multiple road sections. These findings contribute to a more comprehensive approach to surveying road networks. Resume La rugosite d'une route est la deviation de la surface de la route par rapport a la surface concue, qui influence les conditions de securite pour les usagers de la route. Le balayage laser mobile (MLS) offre un moyen rapide, continu et rentable pour recueillir des nuages de points 3D tres precis et denses le long d'une route. Cet article presente un algorithme pour l'estimation automatique de la rugosite de la route a partir de donnees MLS, ou une grille est ajustee sur les points lidar censes representer la surface de la route. La difference entre les altitudes des points lidar et de leurs equivalents dans la grille fournit des valeurs residuelles de hauteur qui peuvent etre utilisees pour estimer la rugosite a la surface de la route. Des tests ont valide ce nouvel algorithme en estimant les caracteristiques de la surface sur de multiples sections de route. Ces resultats contribuent a une approche plus globale du releve topographique des reseaux routiers. Zusammenfassung Die Rauhigkeit einer Strassenoberflache ist die qualitative Abweichung der tatsachlichen Oberflache von der geplanten Oberflache. Eine solche Abweichung beeinflust die Sicherheitsbedingungen fur Strasennutzer. Mit Mobile Laserscanning Systemen (MLS) konnen schnell, kontinuierlich und auf kostengunstige Weise hochgenaue und dichte 3D-Punktwolken entlang eines Strasenkorridors erfasst werden. Dieses Paper stellt einen Algorithmus zur automatischen Bestimmung der Oberflachenrauhigkeit in MLS Daten vor. Ein Oberflachenraster wird an die Punkte der Strasenoberflache angepasst. Die Residuen zwischen Lidarpunkten und den entsprechenden Hohen des angepasten Gitters konnen zur Schatzung der Rauhigkeit verwendet werden. In Tests mit verschiedenen Strasenabschnitten wurde der neue Algorithmus hinsichtlich der Schatzung der Oberflachenbeschaffenheit validiert. Auf Basis dieser Ergebnisse kann ein noch umfassender Ansatz zur Erfassung von ganzen Strasennetzen angegangen werden. Resumen La rugosidad de una carretera es la desviacion de la superficie disenada que afecta las condiciones de seguridad de los usuarios de la carretera. Los sistemas de laser moviles proporcionan una manera rapida, continua y barata de recolectar nubes de puntos 3-D densas y de gran precision a lo largo de un corredor. En este articulo se presenta un algoritmo para la estimacion automatica de la rugosidad de la carretera, donde una malla se ajusta a los puntos lidar asociados con la superficie de la carretera. La diferencia entre la elevacion de los puntos lidar y los equivalentes en la malla proporcionan residuos en altura usados para estimar la rugosidad de la superficie a lo largo de la carretera. Las comprobaciones validan el nuevo algoritmo de rugosidad de la carretera al estimar con exito las condiciones de la carretera en diversas secciones de carretera. Estos resultados contribuyen a un enfoque mas amplio de la medida de las caracteristicas de redes de carreteras. 摘要 路面平整度是衡量道路表面和设计表面之差的等级,对道路使用者的安全条件的度量。移动激光扫描(MLS)系统提供了一种快速获取低成本、高精确和高密度的沿着路线走廊的连续三维点云数据的方式。本文提出从MLS数据自动估计路面平整度的算法,该算法利用一个路面格网来拟合激光点云,两者之间在高程上的残差值可以被用来衡量路面平整度。试验充分验证了本文所提出的新算法针对多路段路面平整度处理的可靠性,本文的这些发现为路网测量提供了一种更全面的手段。
Maynooth University ... arrow_drop_down Maynooth University ePrints & eTheses ArchiveArticle . 2015 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveThe Photogrammetric RecordArticle . 2015 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniSA Research Outputs RepositoryArticle . 2015 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/phor.12090&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 22 citations 22 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Maynooth University ... arrow_drop_down Maynooth University ePrints & eTheses ArchiveArticle . 2015 . Peer-reviewedData sources: Maynooth University ePrints & eTheses ArchiveThe Photogrammetric RecordArticle . 2015 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: CrossrefUniSA Research Outputs RepositoryArticle . 2015 . Peer-reviewedData sources: UniSA Research Outputs Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1111/phor.12090&type=result"></script>'); --> </script>
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