- home
- Search
- Rural Digital Europe
- National Institutes of Health
- UA
- Rural Digital Europe
- National Institutes of Health
- UA
Loading
description Publicationkeyboard_double_arrow_right Article , Preprint , Other literature type 2013 Italy, Croatia, Spain, United States, United Kingdom, Argentina, ArgentinaPublisher:Cold Spring Harbor Laboratory Funded by:NSERC, WT, NSF | XSEDE: eXtreme Science an... +7 projectsNSERC ,WT ,NSF| XSEDE: eXtreme Science and Engineering Discovery Environment ,NIH| Human Genome Structural Variation ,NSF| Collaborative Research: Genetic Bases for the Evolution of Human Diet ,NIH| Population mixture in evolutionary and medical genetics ,NSF| A new history and geography of human genes informed by ancient DNA ,NIH| African Odyssey: An Integrative Genomics Analysis of Complex Physiologic Traits ,EC| MALADAPTED ,NIH| Models of Complex Genetic SystemsIosif Lazaridis; Nick Patterson; Alissa Mittnik; Gabriel Renaud; Swapan Mallick; Karola Kirsanow; Peter H. Sudmant; Joshua G. Schraiber; Sergi Castellano; Mark Lipson; Bonnie Berger; Christos Economou; Ruth Bollongino; Qiaomei Fu; Kirsten I. Bos; Susanne Nordenfelt; Heng Li; Cesare de Filippo; Kay Prüfer; Susanna Sawyer; Cosimo Posth; Wolfgang Haak; Fredrik Hallgren; Elin Fornander; Nadin Rohland; Dominique Delsate; Michael Francken; Jean-Michel Guinet; Joachim Wahl; George Ayodo; Hamza A. Babiker; Graciela Bailliet; Elena Balanovska; Oleg Balanovsky; Ramiro Barrantes; Gabriel Bedoya; Haim Ben-Ami; Judit Bene; Fouad Berrada; Claudio M. Bravi; Francesca Brisighelli; George B.J. Busby; Francesco Calì; Mikhail Churnosov; David E. C. Cole; Daniel Corach; Larissa Damba; George van Driem; Stanislav Dryomov; Jean-Michel Dugoujon; Sardana A. Fedorova; Irene Gallego Romero; Marina Gubina; Michael F. Hammer; Brenna M. Henn; Tor Hervig; Ugur Hodoglugil; Aashish R. Jha; Sena Karachanak-Yankova; Rita Khusainova; Elza Khusnutdinova; Rick A. Kittles; Toomas Kivisild; William Klitz; Vaidutis Kučinskas; Alena Kushniarevich; Leila Laredj; Sergey Litvinov; Theologos Loukidis; Robert W. Mahley; Béla Melegh; Ene Metspalu; Julio Molina; Joanna L. Mountain; Klemetti Näkkäläjärvi; Desislava Nesheva; Thomas B. Nyambo; Ludmila P. Osipova; Jüri Parik; Fedor Platonov; Olga L. Posukh; Valentino Romano; Francisco Rothhammer; Igor Rudan; Ruslan Ruizbakiev; Hovhannes Sahakyan; Antti Sajantila; Antonio Salas; Elena B. Starikovskaya; Ayele Tarekegn; Draga Toncheva; Shahlo Turdikulova; Ingrida Uktveryte; Olga Utevska; René Vasquez; Mercedes Villena; Mikhail Voevoda; Cheryl A. Winkler; Levon Yepiskoposyan; Pierre Zalloua; Tatijana Zemunik; Alan Cooper; Cristian Capelli; Mark G. Thomas; Andres Ruiz-Linares; Sarah A. Tishkoff; Lalji Singh; Kumarasamy Thangaraj; Richard Villems; David Comas; Rem I. Sukernik; Mait Metspalu; Matthias Meyer; Evan E. Eichler; Joachim Burger; Montgomery Slatkin; Svante Pääbo; Janet Kelso; David Reich; Johannes Krause;J. Kr., A.M. and C.P. are grateful for support from DFG grant number KR 4015/1-1, the Carl-Zeiss Foundation and the Baden Württemberg Foundation. S. P., G. R., Q. F., C. F., K. P., S.C. and J.Ke. acknowledge support from the Presidential Innovation Fund of the Max Planck Society. G.R. was supported by an NSERC fellowship. J.G.S. acknowledges use of the Extreme Science and Engineering Discovery Environment (XSEDE), which is supported by NSF grant number OCI-1053575. E.B. and O.B. were supported by RFBR grants 13-06-00670, 13-04-01711, 13-04-90420. B.M. was supported by grants OTKA 73430 and 103983. A.Saj. was supported by a Finnish Professor Pool (Paulo Foundation) Grant. The Lithuanian sampling was supported by the LITGEN project (VP1-3.1-ŠMM-07-K-01-013), funded by the European Social Fund under the Global Grant Measure. A.S. was supported by Spanish grants SAF2011-26983 and EM 2012/045. O.U. was supported by Ukrainian SFFS grant F53.4/071. S.A.T. was supported by NIH Pioneer Award 8DP1ES022577-04 and NSF HOMINID award BCS-0827436. K.T. was supported by an Indian CSIR Network Project (GENESIS: BSC0121). L.S. was supported by an Indian CSIR Bhatnagar Fellowship. R.V., M.M., J.P. and E.M. were supported by the European Union Regional Development Fund through the Centre of Excellence in Genomics to the Estonian Biocentre and University of Tartu and by an Estonian Basic Research grant SF0270177As08. M.M. was additionally supported by Estonian Science Foundation grant number 8973. J.G.S. and M.S. were supported by NIH grant GM40282. P.H.S. and E.E.E. were supported by NIH grants HG004120 and HG002385. D.R. and N.P. were supported by NSF HOMINID award BCS-1032255 and NIH grant GM100233. This project has been funded in part with federal funds from the National Cancer Institute, National Institutes of Health, under contract HHSN26120080001E. This Research was supported in part by the Intramural Research Program of the NIH, National Cancer Institute, Center for Cancer Research We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations' deep relationships and show that early European farmers had ∼44% ancestry from a 'basal Eurasian' population that split before the diversification of other non-African lineages.
bioRxiv arrow_drop_down bioRxivPreprint . 2013Europe PubMed CentralArticle . 2014Full-Text: http://europepmc.org/articles/PMC4170574Data sources: PubMed CentralCONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas; NatureArticle . 2014 . Peer-reviewedLicense: Springer TDMarXiv.org e-Print ArchiveOther literature type . Preprint . 2013Data sources: arXiv.org e-Print ArchiveCroatian Scientific Bibliography - CROSBIArticle . 2014Data sources: Croatian Scientific Bibliography - CROSBIServicio de Difusión de la Creación IntelectualArticle . 2014Data sources: Servicio de Difusión de la Creación Intelectualhttps://doi.org/10.48550/arxiv...Article . 2013License: arXiv Non-Exclusive DistributionData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/001552&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 1K citations 1,096 popularity Top 0.1% influence Top 1% impulse Top 0.1% Powered by BIP!visibility 24visibility views 24 download downloads 297 Powered bymore_vert bioRxiv arrow_drop_down bioRxivPreprint . 2013Europe PubMed CentralArticle . 2014Full-Text: http://europepmc.org/articles/PMC4170574Data sources: PubMed CentralCONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas; NatureArticle . 2014 . Peer-reviewedLicense: Springer TDMarXiv.org e-Print ArchiveOther literature type . Preprint . 2013Data sources: arXiv.org e-Print ArchiveCroatian Scientific Bibliography - CROSBIArticle . 2014Data sources: Croatian Scientific Bibliography - CROSBIServicio de Difusión de la Creación IntelectualArticle . 2014Data sources: Servicio de Difusión de la Creación Intelectualhttps://doi.org/10.48550/arxiv...Article . 2013License: arXiv Non-Exclusive DistributionData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/001552&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2022Publisher:BMJ Funded by:NIH | Studies of Occupational C..., NIH | Health Effects Of Exposur...NIH| Studies of Occupational Cancer (Pesticides) ,NIH| Health Effects Of Exposures In AgricultureSrishti Shrestha; Christine G Parks; David M Umbach; Jonathan N Hofmann; Laura E Beane Freeman; Aaron Blair; Dale P Sandler;ObjectivesPyrethroid insecticides have been linked with multiple health outcomes. One study reported an association with increased all-cause and cardiovascular mortality. Given the widespread use of pyrethroids, these findings warrant confirmation. We explored associations of permethrin/pyrethroid use with overall and cause-specific mortality among 50 665 licensed pesticide applicators in the Agricultural Health Study.MethodsAt enrolment (1993–1997), participants self-reported information on permethrin/pyrethroid use. Information on causes of death came from linkage with death registries through 2016. We used Cox proportional hazards models to estimate HRs and 95% CIs with adjustment for potential confounders.ResultsOver an average 21 years of follow-up, 19.6% (9,955) of the cohort died. We found no clear evidence that ever-use of permethrin/pyrethroid was associated with elevated overall mortality or with mortality from most causes examined. There was suggestive evidence, based on a small number of deaths among those exposed, for elevated pyrethroid-associated mortality from some neurological, respiratory and genitourinary diseases in the overall sample and from lung cancer among never-smokers.ConclusionAlthough based on mortality, which is also affected by survival, rather than incidence, these findings are biologically plausible, and future investigations in other populations may be warranted.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1136/oemed-2021-108156&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 3 citations 3 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1136/oemed-2021-108156&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2015Publisher:Wiley Funded by:NIH | LA Sprouts: A garden/nutr...NIH| LA Sprouts: A garden/nutrition intervention to improve health for high-risk youthAuthors: Gatto, Nicole M.; Martinez, Lauren C.; Spruijt-Metz, Donna; Davis, Jaimie N.;Gatto, Nicole M.; Martinez, Lauren C.; Spruijt-Metz, Donna; Davis, Jaimie N.;ObjectiveTo assess the effects of a 12‐week gardening, nutrition, and cooking intervention (“LA Sprouts”) on dietary intake, obesity parameters, and metabolic disease risk among low‐income, primarily Hispanic/Latino youth in Los Angeles.MethodsThe randomized controlled trial involved four elementary schools [two schools randomized to intervention (172 third–through fifth‐grade students); two schools randomized to control (147 third–through fifth‐grade students)]. Classes were taught in 90‐minute sessions once a week to each grade level for 12 weeks. Data collected at pre‐ and postintervention included dietary intake via food frequency questionnaire (FFQ), anthropometric measures [BMI, waist circumference (WC)], body fat, and fasting blood samples.ResultsLA Sprouts participants had significantly greater reductions in BMI z‐scores (0.1‐vs. 0.04‐point decrease, respectively; P = 0.01) and WC (−1.2 cm vs. no change; P < 0.001). Fewer LA Sprouts participants had the metabolic syndrome (MetSyn) after the intervention than before, while the number of controls with MetSyn increased. LA Sprouts participants had improvements in dietary fiber intake (+3.5% vs. −15.5%; P = 0.04) and less decreases in vegetable intake (−3.6% vs. −26.4%; P = 0.04). Change in fruit intake before and after the intervention did not significantly differ between LA Sprouts and control subjects.ConclusionsLA Sprouts was effective in reducing obesity and metabolic risk.
Obesity arrow_drop_down ObesityArticle . 2015Full-Text: http://europepmc.org/articles/PMC4446151Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1002/oby.21077&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 24 citations 24 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!visibility 1visibility views 1 Powered bymore_vert Obesity arrow_drop_down ObesityArticle . 2015Full-Text: http://europepmc.org/articles/PMC4446151Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1002/oby.21077&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2018Publisher:Public Library of Science (PLoS) Funded by:NIH | Caenorhabditis Genetics C...NIH| Caenorhabditis Genetics CenterAuthors: Saad M. Alzahrani; Paul R. Ebert;Saad M. Alzahrani; Paul R. Ebert;Phosphine is the only general use fumigant for the protection of stored grain, though its long-term utility is threatened by the emergence of highly phosphine-resistant pests. Given this precarious situation, it is essential to identify factors, such as stress preconditioning, that interfere with the efficacy of phosphine fumigation. We used Caenorhabditis elegans as a model organism to test the effect of pre-exposure to heat and cold shock, UV and gamma irradiation on phosphine potency. Heat shock significantly increased tolerance to phosphine by 3-fold in wild-type nematodes, a process that was dependent on the master regulator of the heat shock response, HSF-1. Heat shock did not, however, increase the resistance of a strain carrying the phosphine resistance mutation, dld-1(wr4), and cold shock did not alter the response to phosphine of either strain. Pretreatment with the LD50 of UV (18 J cm-2) did not alter phosphine tolerance in wild-type nematodes, but the LD50 (33 J cm-2) of the phosphine resistant strain (dld-1(wr4)) doubled the level of resistance. In addition, exposure to a mild dose of gamma radiation (200 Gy) elevated the phosphine tolerance by ~2-fold in both strains.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC5909616Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0195349&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 10 citations 10 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC5909616Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0195349&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint 2017 France, Italy, Croatia, United Kingdom, CroatiaPublisher:Cold Spring Harbor Laboratory Publicly fundedFunded by:EC | CROSSROADS, NIH | Population mixture in evo..., EC | ADNABIOARC +5 projectsEC| CROSSROADS ,NIH| Population mixture in evolutionary and medical genetics ,EC| ADNABIOARC ,EC| PAGE ,NSF| Investigating The Relationship Between Climate Change And Social Organization In A Small Scale Society ,HRZZ| Rekonstrukcija prapovijesnog (od neolitika do brončanog doba) načina života na području Hrvatske – multidisciplinarni pristup ,IRC ,NSF| A new history and geography of human genes informed by ancient DNAAuthors: Iain Mathieson; Songül Alpaslan-Roodenberg; Cosimo Posth; Anna Szécsényi-Nagy; +113 AuthorsIain Mathieson; Songül Alpaslan-Roodenberg; Cosimo Posth; Anna Szécsényi-Nagy; Nadin Rohland; Swapan Mallick; Iñigo Olalde; Nasreen Broomandkhoshbacht; Francesca Candilio; Olivia Cheronet; Daniel Fernandes; Matthew Ferry; Beatriz Gamarra; Gloria G. Fortes; Wolfgang Haak; Eadaoin Harney; Eppie R. Jones; Denise Keating; Ben Krause-Kyora; Isil Kucukkalipci; Megan Michel; Alissa Mittnik; Kathrin Nägele; Mario Novak; Jonas Oppenheimer; Nick Patterson; Saskia Pfrengle; Kendra Sirak; Kristin Stewardson; Stefania Vai; Stefan Alexandrov; Kurt W. Alt; Radian Andreescu; Dragana Antonović; Abigail Ash; Nadezhda Atanassova; Krum Bacvarov; Mende Balázs Gusztáv; Hervé Bocherens; Michael Bolus; Adina Boroneanţ; Yavor Boyadzhiev; Alicja Budnik; Josip Burmaz; Stefan Chohadzhiev; Nicholas J. Conard; Richard Cottiaux; Maja Čuka; Christophe Cupillard; Dorothée G. Drucker; Nedko Elenski; Michael Francken; Borislava Galabova; Georgi Ganetsovski; Bernard Gély; Tamás Hajdu; Veneta Handzhyiska; Katerina Harvati; Thomas Higham; Stanislav Iliev; Ivor Janković; Ivor Karavanić; Douglas J. Kennett; Darko Komšo; Alexandra Kozak; Damian Labuda; Martina Lari; Cătălin Lazăr; Maleen Leppek; Krassimir Leshtakov; Domenico Lo Vetro; Dženi Los; Ivaylo Lozanov; Maria Malina; Fabio Martini; Kath McSweeney; Harald Meller; Marko Menđušić; Pavel Mirea; Vyacheslav Moiseyev; Vanya Petrova; T. Douglas Price; Angela Simalcsik; Luca Sineo; Mario Šlaus; Vladimir Slavchev; Petar Stanev; Andrej Starović; Tamás Szeniczey; Sahra Talamo; Maria Teschler-Nicola; Corinne Thevenet; Ivan Valchev; Frédérique Valentin; Sergey Vasilyev; Fanica Veljanovska; Svetlana Venelinova; Elizaveta Veselovskaya; Bence Viola; Cristian Virag; Joško Zaninović; Steve Zäuner; Philipp W. Stockhammer; Giulio Catalano; Raiko Krauß; David Caramelli; Gunita Zariņa; Bisserka Gaydarska; Malcolm Lillie; Alexey G. Nikitin; Inna Potekhina; Anastasia Papathanasiou; Dusan Boric; Clive Bonsall; Johannes Krause; Ron Pinhasi; David Reich;handle: 11585/700884 , 20.500.11820/7e7e9932-e09a-43e6-b2ce-c921975286e8 , 11392/2418484 , 2158/1100235 , 11573/1083033
pmc: PMC6091220
pmid: 29466330
handle: 11585/700884 , 20.500.11820/7e7e9932-e09a-43e6-b2ce-c921975286e8 , 11392/2418484 , 2158/1100235 , 11573/1083033
pmc: PMC6091220
pmid: 29466330
Farming was first introduced to southeastern Europe in the mid-7th millennium BCE - brought by migrants from Anatolia who settled in the region before spreading throughout Europe. However, the dynamics of the interaction between the first farmers and the indigenous hunter-gatherers remain poorly understood because of the near absence of ancient DNA from the region. We report new genome-wide ancient DNA data from 204 individuals-65 Paleolithic and Mesolithic, 93 Neolithic, and 46 Copper, Bronze and Iron Age-who lived in southeastern Europe and surrounding regions between about 12,000 and 500 BCE. We document that the hunter-gatherer populations of southeastern Europe, the Baltic, and the North Pontic Steppe were distinctive from those of western Europe, with a West-East cline of ancestry. We show that the people who brought farming to Europe were not part of a single population, as early farmers from southern Greece are not descended from the Neolithic population of northwestern Anatolia that was ancestral to all other European farmers. The ancestors of the first farmers of northern and western Europe passed through southeastern Europe with limited admixture with local hunter-gatherers, but we show that some groups that remained in the region mixed extensively with local hunter-gatherers, with relatively sex-balanced admixture compared to the male-biased hunter-gatherer admixture that we show prevailed later in the North and West. After the spread of farming, southeastern Europe continued to be a nexus between East and West, with intermittent steppe ancestry, including in individuals from the Varna I cemetery and associated with the Cucuteni-Trypillian archaeological complex, up to 2,000 years before the Steppe migration that replaced much of northern Europe9s population.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6091220Data sources: PubMed CentralbioRxivPreprint . 2017ODRAZ - Open Repository of the University of Zagreb Faculty of Humanities and Social SciencesOther literature type . Article . 2018License: CC BYArchivio della ricerca- Università di Roma La SapienzaArticle . 2018Data sources: Archivio della ricerca- Università di Roma La SapienzaCroatian Scientific Bibliography - CROSBIArticle . 2018Data sources: Croatian Scientific Bibliography - CROSBIMémoires en Sciences de l'Information et de la CommunicationArticle . 2018Full-Text: https://hal.science/hal-03339006/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/135616&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 455 citations 455 popularity Top 0.1% influence Top 1% impulse Top 0.1% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6091220Data sources: PubMed CentralbioRxivPreprint . 2017ODRAZ - Open Repository of the University of Zagreb Faculty of Humanities and Social SciencesOther literature type . Article . 2018License: CC BYArchivio della ricerca- Università di Roma La SapienzaArticle . 2018Data sources: Archivio della ricerca- Università di Roma La SapienzaCroatian Scientific Bibliography - CROSBIArticle . 2018Data sources: Croatian Scientific Bibliography - CROSBIMémoires en Sciences de l'Information et de la CommunicationArticle . 2018Full-Text: https://hal.science/hal-03339006/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/135616&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu
Loading
description Publicationkeyboard_double_arrow_right Article , Preprint , Other literature type 2013 Italy, Croatia, Spain, United States, United Kingdom, Argentina, ArgentinaPublisher:Cold Spring Harbor Laboratory Funded by:NSERC, WT, NSF | XSEDE: eXtreme Science an... +7 projectsNSERC ,WT ,NSF| XSEDE: eXtreme Science and Engineering Discovery Environment ,NIH| Human Genome Structural Variation ,NSF| Collaborative Research: Genetic Bases for the Evolution of Human Diet ,NIH| Population mixture in evolutionary and medical genetics ,NSF| A new history and geography of human genes informed by ancient DNA ,NIH| African Odyssey: An Integrative Genomics Analysis of Complex Physiologic Traits ,EC| MALADAPTED ,NIH| Models of Complex Genetic SystemsIosif Lazaridis; Nick Patterson; Alissa Mittnik; Gabriel Renaud; Swapan Mallick; Karola Kirsanow; Peter H. Sudmant; Joshua G. Schraiber; Sergi Castellano; Mark Lipson; Bonnie Berger; Christos Economou; Ruth Bollongino; Qiaomei Fu; Kirsten I. Bos; Susanne Nordenfelt; Heng Li; Cesare de Filippo; Kay Prüfer; Susanna Sawyer; Cosimo Posth; Wolfgang Haak; Fredrik Hallgren; Elin Fornander; Nadin Rohland; Dominique Delsate; Michael Francken; Jean-Michel Guinet; Joachim Wahl; George Ayodo; Hamza A. Babiker; Graciela Bailliet; Elena Balanovska; Oleg Balanovsky; Ramiro Barrantes; Gabriel Bedoya; Haim Ben-Ami; Judit Bene; Fouad Berrada; Claudio M. Bravi; Francesca Brisighelli; George B.J. Busby; Francesco Calì; Mikhail Churnosov; David E. C. Cole; Daniel Corach; Larissa Damba; George van Driem; Stanislav Dryomov; Jean-Michel Dugoujon; Sardana A. Fedorova; Irene Gallego Romero; Marina Gubina; Michael F. Hammer; Brenna M. Henn; Tor Hervig; Ugur Hodoglugil; Aashish R. Jha; Sena Karachanak-Yankova; Rita Khusainova; Elza Khusnutdinova; Rick A. Kittles; Toomas Kivisild; William Klitz; Vaidutis Kučinskas; Alena Kushniarevich; Leila Laredj; Sergey Litvinov; Theologos Loukidis; Robert W. Mahley; Béla Melegh; Ene Metspalu; Julio Molina; Joanna L. Mountain; Klemetti Näkkäläjärvi; Desislava Nesheva; Thomas B. Nyambo; Ludmila P. Osipova; Jüri Parik; Fedor Platonov; Olga L. Posukh; Valentino Romano; Francisco Rothhammer; Igor Rudan; Ruslan Ruizbakiev; Hovhannes Sahakyan; Antti Sajantila; Antonio Salas; Elena B. Starikovskaya; Ayele Tarekegn; Draga Toncheva; Shahlo Turdikulova; Ingrida Uktveryte; Olga Utevska; René Vasquez; Mercedes Villena; Mikhail Voevoda; Cheryl A. Winkler; Levon Yepiskoposyan; Pierre Zalloua; Tatijana Zemunik; Alan Cooper; Cristian Capelli; Mark G. Thomas; Andres Ruiz-Linares; Sarah A. Tishkoff; Lalji Singh; Kumarasamy Thangaraj; Richard Villems; David Comas; Rem I. Sukernik; Mait Metspalu; Matthias Meyer; Evan E. Eichler; Joachim Burger; Montgomery Slatkin; Svante Pääbo; Janet Kelso; David Reich; Johannes Krause;J. Kr., A.M. and C.P. are grateful for support from DFG grant number KR 4015/1-1, the Carl-Zeiss Foundation and the Baden Württemberg Foundation. S. P., G. R., Q. F., C. F., K. P., S.C. and J.Ke. acknowledge support from the Presidential Innovation Fund of the Max Planck Society. G.R. was supported by an NSERC fellowship. J.G.S. acknowledges use of the Extreme Science and Engineering Discovery Environment (XSEDE), which is supported by NSF grant number OCI-1053575. E.B. and O.B. were supported by RFBR grants 13-06-00670, 13-04-01711, 13-04-90420. B.M. was supported by grants OTKA 73430 and 103983. A.Saj. was supported by a Finnish Professor Pool (Paulo Foundation) Grant. The Lithuanian sampling was supported by the LITGEN project (VP1-3.1-ŠMM-07-K-01-013), funded by the European Social Fund under the Global Grant Measure. A.S. was supported by Spanish grants SAF2011-26983 and EM 2012/045. O.U. was supported by Ukrainian SFFS grant F53.4/071. S.A.T. was supported by NIH Pioneer Award 8DP1ES022577-04 and NSF HOMINID award BCS-0827436. K.T. was supported by an Indian CSIR Network Project (GENESIS: BSC0121). L.S. was supported by an Indian CSIR Bhatnagar Fellowship. R.V., M.M., J.P. and E.M. were supported by the European Union Regional Development Fund through the Centre of Excellence in Genomics to the Estonian Biocentre and University of Tartu and by an Estonian Basic Research grant SF0270177As08. M.M. was additionally supported by Estonian Science Foundation grant number 8973. J.G.S. and M.S. were supported by NIH grant GM40282. P.H.S. and E.E.E. were supported by NIH grants HG004120 and HG002385. D.R. and N.P. were supported by NSF HOMINID award BCS-1032255 and NIH grant GM100233. This project has been funded in part with federal funds from the National Cancer Institute, National Institutes of Health, under contract HHSN26120080001E. This Research was supported in part by the Intramural Research Program of the NIH, National Cancer Institute, Center for Cancer Research We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old hunter-gatherers from Luxembourg and Sweden. We analysed these and other ancient genomes with 2,345 contemporary humans to show that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunter-gatherer related ancestry. We model these populations' deep relationships and show that early European farmers had ∼44% ancestry from a 'basal Eurasian' population that split before the diversification of other non-African lineages.
bioRxiv arrow_drop_down bioRxivPreprint . 2013Europe PubMed CentralArticle . 2014Full-Text: http://europepmc.org/articles/PMC4170574Data sources: PubMed CentralCONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas; NatureArticle . 2014 . Peer-reviewedLicense: Springer TDMarXiv.org e-Print ArchiveOther literature type . Preprint . 2013Data sources: arXiv.org e-Print ArchiveCroatian Scientific Bibliography - CROSBIArticle . 2014Data sources: Croatian Scientific Bibliography - CROSBIServicio de Difusión de la Creación IntelectualArticle . 2014Data sources: Servicio de Difusión de la Creación Intelectualhttps://doi.org/10.48550/arxiv...Article . 2013License: arXiv Non-Exclusive DistributionData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/001552&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 1K citations 1,096 popularity Top 0.1% influence Top 1% impulse Top 0.1% Powered by BIP!visibility 24visibility views 24 download downloads 297 Powered bymore_vert bioRxiv arrow_drop_down bioRxivPreprint . 2013Europe PubMed CentralArticle . 2014Full-Text: http://europepmc.org/articles/PMC4170574Data sources: PubMed CentralCONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas; NatureArticle . 2014 . Peer-reviewedLicense: Springer TDMarXiv.org e-Print ArchiveOther literature type . Preprint . 2013Data sources: arXiv.org e-Print ArchiveCroatian Scientific Bibliography - CROSBIArticle . 2014Data sources: Croatian Scientific Bibliography - CROSBIServicio de Difusión de la Creación IntelectualArticle . 2014Data sources: Servicio de Difusión de la Creación Intelectualhttps://doi.org/10.48550/arxiv...Article . 2013License: arXiv Non-Exclusive DistributionData sources: Dataciteadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/001552&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2022Publisher:BMJ Funded by:NIH | Studies of Occupational C..., NIH | Health Effects Of Exposur...NIH| Studies of Occupational Cancer (Pesticides) ,NIH| Health Effects Of Exposures In AgricultureSrishti Shrestha; Christine G Parks; David M Umbach; Jonathan N Hofmann; Laura E Beane Freeman; Aaron Blair; Dale P Sandler;ObjectivesPyrethroid insecticides have been linked with multiple health outcomes. One study reported an association with increased all-cause and cardiovascular mortality. Given the widespread use of pyrethroids, these findings warrant confirmation. We explored associations of permethrin/pyrethroid use with overall and cause-specific mortality among 50 665 licensed pesticide applicators in the Agricultural Health Study.MethodsAt enrolment (1993–1997), participants self-reported information on permethrin/pyrethroid use. Information on causes of death came from linkage with death registries through 2016. We used Cox proportional hazards models to estimate HRs and 95% CIs with adjustment for potential confounders.ResultsOver an average 21 years of follow-up, 19.6% (9,955) of the cohort died. We found no clear evidence that ever-use of permethrin/pyrethroid was associated with elevated overall mortality or with mortality from most causes examined. There was suggestive evidence, based on a small number of deaths among those exposed, for elevated pyrethroid-associated mortality from some neurological, respiratory and genitourinary diseases in the overall sample and from lung cancer among never-smokers.ConclusionAlthough based on mortality, which is also affected by survival, rather than incidence, these findings are biologically plausible, and future investigations in other populations may be warranted.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1136/oemed-2021-108156&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 3 citations 3 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1136/oemed-2021-108156&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2015Publisher:Wiley Funded by:NIH | LA Sprouts: A garden/nutr...NIH| LA Sprouts: A garden/nutrition intervention to improve health for high-risk youthAuthors: Gatto, Nicole M.; Martinez, Lauren C.; Spruijt-Metz, Donna; Davis, Jaimie N.;Gatto, Nicole M.; Martinez, Lauren C.; Spruijt-Metz, Donna; Davis, Jaimie N.;ObjectiveTo assess the effects of a 12‐week gardening, nutrition, and cooking intervention (“LA Sprouts”) on dietary intake, obesity parameters, and metabolic disease risk among low‐income, primarily Hispanic/Latino youth in Los Angeles.MethodsThe randomized controlled trial involved four elementary schools [two schools randomized to intervention (172 third–through fifth‐grade students); two schools randomized to control (147 third–through fifth‐grade students)]. Classes were taught in 90‐minute sessions once a week to each grade level for 12 weeks. Data collected at pre‐ and postintervention included dietary intake via food frequency questionnaire (FFQ), anthropometric measures [BMI, waist circumference (WC)], body fat, and fasting blood samples.ResultsLA Sprouts participants had significantly greater reductions in BMI z‐scores (0.1‐vs. 0.04‐point decrease, respectively; P = 0.01) and WC (−1.2 cm vs. no change; P < 0.001). Fewer LA Sprouts participants had the metabolic syndrome (MetSyn) after the intervention than before, while the number of controls with MetSyn increased. LA Sprouts participants had improvements in dietary fiber intake (+3.5% vs. −15.5%; P = 0.04) and less decreases in vegetable intake (−3.6% vs. −26.4%; P = 0.04). Change in fruit intake before and after the intervention did not significantly differ between LA Sprouts and control subjects.ConclusionsLA Sprouts was effective in reducing obesity and metabolic risk.
Obesity arrow_drop_down ObesityArticle . 2015Full-Text: http://europepmc.org/articles/PMC4446151Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1002/oby.21077&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 24 citations 24 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!visibility 1visibility views 1 Powered bymore_vert Obesity arrow_drop_down ObesityArticle . 2015Full-Text: http://europepmc.org/articles/PMC4446151Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1002/oby.21077&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2018Publisher:Public Library of Science (PLoS) Funded by:NIH | Caenorhabditis Genetics C...NIH| Caenorhabditis Genetics CenterAuthors: Saad M. Alzahrani; Paul R. Ebert;Saad M. Alzahrani; Paul R. Ebert;Phosphine is the only general use fumigant for the protection of stored grain, though its long-term utility is threatened by the emergence of highly phosphine-resistant pests. Given this precarious situation, it is essential to identify factors, such as stress preconditioning, that interfere with the efficacy of phosphine fumigation. We used Caenorhabditis elegans as a model organism to test the effect of pre-exposure to heat and cold shock, UV and gamma irradiation on phosphine potency. Heat shock significantly increased tolerance to phosphine by 3-fold in wild-type nematodes, a process that was dependent on the master regulator of the heat shock response, HSF-1. Heat shock did not, however, increase the resistance of a strain carrying the phosphine resistance mutation, dld-1(wr4), and cold shock did not alter the response to phosphine of either strain. Pretreatment with the LD50 of UV (18 J cm-2) did not alter phosphine tolerance in wild-type nematodes, but the LD50 (33 J cm-2) of the phosphine resistant strain (dld-1(wr4)) doubled the level of resistance. In addition, exposure to a mild dose of gamma radiation (200 Gy) elevated the phosphine tolerance by ~2-fold in both strains.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC5909616Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0195349&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 10 citations 10 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC5909616Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1371/journal.pone.0195349&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint 2017 France, Italy, Croatia, United Kingdom, CroatiaPublisher:Cold Spring Harbor Laboratory Publicly fundedFunded by:EC | CROSSROADS, NIH | Population mixture in evo..., EC | ADNABIOARC +5 projectsEC| CROSSROADS ,NIH| Population mixture in evolutionary and medical genetics ,EC| ADNABIOARC ,EC| PAGE ,NSF| Investigating The Relationship Between Climate Change And Social Organization In A Small Scale Society ,HRZZ| Rekonstrukcija prapovijesnog (od neolitika do brončanog doba) načina života na području Hrvatske – multidisciplinarni pristup ,IRC ,NSF| A new history and geography of human genes informed by ancient DNAAuthors: Iain Mathieson; Songül Alpaslan-Roodenberg; Cosimo Posth; Anna Szécsényi-Nagy; +113 AuthorsIain Mathieson; Songül Alpaslan-Roodenberg; Cosimo Posth; Anna Szécsényi-Nagy; Nadin Rohland; Swapan Mallick; Iñigo Olalde; Nasreen Broomandkhoshbacht; Francesca Candilio; Olivia Cheronet; Daniel Fernandes; Matthew Ferry; Beatriz Gamarra; Gloria G. Fortes; Wolfgang Haak; Eadaoin Harney; Eppie R. Jones; Denise Keating; Ben Krause-Kyora; Isil Kucukkalipci; Megan Michel; Alissa Mittnik; Kathrin Nägele; Mario Novak; Jonas Oppenheimer; Nick Patterson; Saskia Pfrengle; Kendra Sirak; Kristin Stewardson; Stefania Vai; Stefan Alexandrov; Kurt W. Alt; Radian Andreescu; Dragana Antonović; Abigail Ash; Nadezhda Atanassova; Krum Bacvarov; Mende Balázs Gusztáv; Hervé Bocherens; Michael Bolus; Adina Boroneanţ; Yavor Boyadzhiev; Alicja Budnik; Josip Burmaz; Stefan Chohadzhiev; Nicholas J. Conard; Richard Cottiaux; Maja Čuka; Christophe Cupillard; Dorothée G. Drucker; Nedko Elenski; Michael Francken; Borislava Galabova; Georgi Ganetsovski; Bernard Gély; Tamás Hajdu; Veneta Handzhyiska; Katerina Harvati; Thomas Higham; Stanislav Iliev; Ivor Janković; Ivor Karavanić; Douglas J. Kennett; Darko Komšo; Alexandra Kozak; Damian Labuda; Martina Lari; Cătălin Lazăr; Maleen Leppek; Krassimir Leshtakov; Domenico Lo Vetro; Dženi Los; Ivaylo Lozanov; Maria Malina; Fabio Martini; Kath McSweeney; Harald Meller; Marko Menđušić; Pavel Mirea; Vyacheslav Moiseyev; Vanya Petrova; T. Douglas Price; Angela Simalcsik; Luca Sineo; Mario Šlaus; Vladimir Slavchev; Petar Stanev; Andrej Starović; Tamás Szeniczey; Sahra Talamo; Maria Teschler-Nicola; Corinne Thevenet; Ivan Valchev; Frédérique Valentin; Sergey Vasilyev; Fanica Veljanovska; Svetlana Venelinova; Elizaveta Veselovskaya; Bence Viola; Cristian Virag; Joško Zaninović; Steve Zäuner; Philipp W. Stockhammer; Giulio Catalano; Raiko Krauß; David Caramelli; Gunita Zariņa; Bisserka Gaydarska; Malcolm Lillie; Alexey G. Nikitin; Inna Potekhina; Anastasia Papathanasiou; Dusan Boric; Clive Bonsall; Johannes Krause; Ron Pinhasi; David Reich;handle: 11585/700884 , 20.500.11820/7e7e9932-e09a-43e6-b2ce-c921975286e8 , 11392/2418484 , 2158/1100235 , 11573/1083033
pmc: PMC6091220
pmid: 29466330
handle: 11585/700884 , 20.500.11820/7e7e9932-e09a-43e6-b2ce-c921975286e8 , 11392/2418484 , 2158/1100235 , 11573/1083033
pmc: PMC6091220
pmid: 29466330
Farming was first introduced to southeastern Europe in the mid-7th millennium BCE - brought by migrants from Anatolia who settled in the region before spreading throughout Europe. However, the dynamics of the interaction between the first farmers and the indigenous hunter-gatherers remain poorly understood because of the near absence of ancient DNA from the region. We report new genome-wide ancient DNA data from 204 individuals-65 Paleolithic and Mesolithic, 93 Neolithic, and 46 Copper, Bronze and Iron Age-who lived in southeastern Europe and surrounding regions between about 12,000 and 500 BCE. We document that the hunter-gatherer populations of southeastern Europe, the Baltic, and the North Pontic Steppe were distinctive from those of western Europe, with a West-East cline of ancestry. We show that the people who brought farming to Europe were not part of a single population, as early farmers from southern Greece are not descended from the Neolithic population of northwestern Anatolia that was ancestral to all other European farmers. The ancestors of the first farmers of northern and western Europe passed through southeastern Europe with limited admixture with local hunter-gatherers, but we show that some groups that remained in the region mixed extensively with local hunter-gatherers, with relatively sex-balanced admixture compared to the male-biased hunter-gatherer admixture that we show prevailed later in the North and West. After the spread of farming, southeastern Europe continued to be a nexus between East and West, with intermittent steppe ancestry, including in individuals from the Varna I cemetery and associated with the Cucuteni-Trypillian archaeological complex, up to 2,000 years before the Steppe migration that replaced much of northern Europe9s population.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6091220Data sources: PubMed CentralbioRxivPreprint . 2017ODRAZ - Open Repository of the University of Zagreb Faculty of Humanities and Social SciencesOther literature type . Article . 2018License: CC BYArchivio della ricerca- Università di Roma La SapienzaArticle . 2018Data sources: Archivio della ricerca- Università di Roma La SapienzaCroatian Scientific Bibliography - CROSBIArticle . 2018Data sources: Croatian Scientific Bibliography - CROSBIMémoires en Sciences de l'Information et de la CommunicationArticle . 2018Full-Text: https://hal.science/hal-03339006/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/135616&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 455 citations 455 popularity Top 0.1% influence Top 1% impulse Top 0.1% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6091220Data sources: PubMed CentralbioRxivPreprint . 2017ODRAZ - Open Repository of the University of Zagreb Faculty of Humanities and Social SciencesOther literature type . Article . 2018License: CC BYArchivio della ricerca- Università di Roma La SapienzaArticle . 2018Data sources: Archivio della ricerca- Università di Roma La SapienzaCroatian Scientific Bibliography - CROSBIArticle . 2018Data sources: Croatian Scientific Bibliography - CROSBIMémoires en Sciences de l'Information et de la CommunicationArticle . 2018Full-Text: https://hal.science/hal-03339006/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/135616&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu