• CH

  • A repository of glycans with associated MS information and spectra. The repository allows researcher to submit their glycomics MS data for public display. The data is not curated by other than then data provider. Curated data will be transfered to UniCarb-DR

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  • Alternative cleavage and polyadenylation (APA) of RNAs gives rise to isoforms with different terminal exons, which in turn determine the fate of the RNA and the encoded protein. APA has thus been implicated in the regulation of cell proliferation, differentiation and disease development. PolyASite is a portal to the curated set of poly(A) sites inferred from publicly available 3’ end sequencing datasets. It allows efficient finding, exploration and export of poly(A) sites in several organisms. In constructing our poly(A) site atlas, we applied uniform quality measures, including the flagging of putative internal priming sites, to input datasets originating from different 3’ end sequencing techniques, cell types or tissues. Through integrated processing of all data, we identified and clustered sites that are closely spaced and share polyadenylation signals, as these are likely the result of stochastic variations in processing. For each cluster, we identified the representative - most frequently processed - site and estimated the relative use in the transcriptome across all samples. While other existing alternative polyadenylation databases rely on a single experimental method, or on poly(A) site estimation from RNA-seq data, PolyASite is built on data from several 3’ end sequencing techniques. This allows a broader coverage of cell types and poly(A) sites to support further genomics studies.

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  • The Ashbya Genome Database (AGD) is a genome/transcriptome database containing gene annotation and high-density oligonucleotide microarray expression data for protein-coding genes from Ashbya gossypii and the model organism Saccharomyces cerevisiae.

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  • ViralZone is a web resource for viral genes and families, providing detailed molecular and epidemiological information, along with virion and genome figures. Each virus or family page gives easy access to UniProtKB/Swiss-Prot viral protein entries.

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  • PROSITE is a database of protein families and domains. PROSITE consists of documentation entries describing protein domains, families and functional sites as well as associated patterns and profiles to identify them.

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  • A repository of glycans with associated MS information and spectra. The repository allows researcher to submit their glycomics MS data for public display. The data is not curated by other than then data provider. Curated data will be transfered to UniCarb-DR

    more_vert
  • more_vert
  • more_vert
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  • Alternative cleavage and polyadenylation (APA) of RNAs gives rise to isoforms with different terminal exons, which in turn determine the fate of the RNA and the encoded protein. APA has thus been implicated in the regulation of cell proliferation, differentiation and disease development. PolyASite is a portal to the curated set of poly(A) sites inferred from publicly available 3’ end sequencing datasets. It allows efficient finding, exploration and export of poly(A) sites in several organisms. In constructing our poly(A) site atlas, we applied uniform quality measures, including the flagging of putative internal priming sites, to input datasets originating from different 3’ end sequencing techniques, cell types or tissues. Through integrated processing of all data, we identified and clustered sites that are closely spaced and share polyadenylation signals, as these are likely the result of stochastic variations in processing. For each cluster, we identified the representative - most frequently processed - site and estimated the relative use in the transcriptome across all samples. While other existing alternative polyadenylation databases rely on a single experimental method, or on poly(A) site estimation from RNA-seq data, PolyASite is built on data from several 3’ end sequencing techniques. This allows a broader coverage of cell types and poly(A) sites to support further genomics studies.

    more_vert
  • The Ashbya Genome Database (AGD) is a genome/transcriptome database containing gene annotation and high-density oligonucleotide microarray expression data for protein-coding genes from Ashbya gossypii and the model organism Saccharomyces cerevisiae.

    more_vert
  • ViralZone is a web resource for viral genes and families, providing detailed molecular and epidemiological information, along with virion and genome figures. Each virus or family page gives easy access to UniProtKB/Swiss-Prot viral protein entries.

    more_vert
  • more_vert
  • more_vert
  • PROSITE is a database of protein families and domains. PROSITE consists of documentation entries describing protein domains, families and functional sites as well as associated patterns and profiles to identify them.

    more_vert